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Sherlock Holmes, fresh out of rehab, is teamed with a sobriety partner, a former surgeon named Watson. They have to learn to work together even as they tackle their first case, the mysterious death of a doctor's wife.

Two heirs of a fortune are murder suspects, but one sister has an undeniable alibi and the other is a coma patient. Holmes is baffled as to how a coma patient could be the killer until another addict in his support group gives him...

Holmes is excited to be consulted about the latest strike of 'balloon man', a serial killer who focuses on children. Analyzing the crime scene, Holmes' deductions lead to the recovery of the first victim, Adam Kemper (then 12, now...

During a visit to a hospital's morgue to do some experiments, Holmes deduces that a terminally ill patient has been murdered. Is this an isolated incident or is there an "Angel of Death" operating in the hospital?

After a small jet crashes killing four people, Holmes battles both the police and the NTSB when he believes one of them was murdered before the crash occurred. Meanwhile, Watson confronts Holmes over a past friend, someone named I...

Sherlock identifies new murders as the modus operandi of Wade Crewes, the serial killer whose arrest made Captain Thomas Gregson's NYPD career. Their friendship is strained by necessary questions of whether it's a copycat, a forme...

While Watson struggles with Holmes over finding a new sponsor, they work a case of a bombing of an Internet company. The bomb was planted four years ago but it's inconceivable that anyone would plan a bombing so far into the future.

Oriental studies professor Trent Annunzio was killed with a bullet in each eye. Sherlock works out he was a Mahjong gambling addict and in which establishment, where he forces the owner to hand over secret video recordings. Those ...

Micah Erlich hires Holmes to solve urgently the robbery of diamonds in David Batonvert's Manhattan exchange from his world-reputed security firm's top-range vault model, the 'impregnable' Leviathan, before the news wrecks the manu...

The manager of a high-end hotel that caters to diplomatic VIPs is found dead in the hotel's laundry. After first suspecting a connection to a prostitution ring, Holmes believes the answer lies in her treacherous past.

Sherlock is called in on a case and immediately recognizes the work of an old foe from Britain. Sherlock sees it as a chance at redemption in catching the man, but first he needs to control his own emotions about the murderer.

Holmes discovers a man running an internet conspiracy site is dead. As he follows the chain of clues, he becomes aware of the "Red Team" and the trail leads him further down the rabbit hole than he ever imagined.

A convicted killer who is supposed to donate a kidney to his sister ends up killing the surgical staff before escaping. Holmes is forced to work with a profiler (whom he can't stand) because she supposedly can predict what he will...

Holmes' former drug supplier comes to him for help to find his kidnapped daughter. He agrees to help him despite Watson's protests. When Holmes appears stymied, the former dealer encourages Holmes to go back on drugs, hoping it wi...

Detective Bell is nearly killed while driving home one night. A just-released felon is the first suspect but, when he's killed, suspicion moves to Bell's brother who, unlike the dedicated detective, has lived life on the wrong sid...

A wealthy scientist comes to Holmes with a unique case: he believes he has been "poisoned" with a genetic disorder. Holmes has to determine how a healthy person can be contaminated with a genetic disease that no one in his family ...

Watson works a case on her own about a woman who has disappeared while Holmes deals with a subway murder. As they work their separate cases they gradually appear to be connected, even though they can't determine exactly how.

In the middle of a winter storm, Holmes and Watson must solve the murder of a guard during a botched robbery and unravel the killer's true plan. The pair also get an interesting new roommate.

A blackmailer uses tapes of underage girls to get money from their fathers. When Holmes witnesses the blackmailer's murder, it becomes a race to find out who his accomplice is and prevent the videos from being released on the Inte...

A man connected to the classification of a valuable building as a landmark trust dies when his pacemaker is deliberately short circuited. Holmes soon learns the one behind the murder is an old nemesis known to him only as "Moriarty".

Moriarty asks Holmes to find out who murdered a mechanic in Brooklyn. Despite Watson's protests, Holmes thinks this case will help him uncover Moriarty's true identity, but it will, in fact, lead Holmes to something much worse.

Holmes reconnects with Irene, his one true love that he thought had been taken from him by Moriarity. He tries to protect her as she recovers from her trauma but he soon learns that it isn't she that needs protection.

Holmes and Watson travel to London to help track down an old mentor and investigate an unsolved mystery.

When a well-respected mathematician is found dead, Holmes and Watson set out to solve a murder and the purpose of the highly guarded equation he was trying to decipher.

When Holmes and Watson set out to track down a civil contractor who leaked classified information, their lives are disrupted when they are targeted by the group of cyber-activists protecting him. Tony Award Winner Steve Kazee gues...

When dominatrix friend of Sherlock's finds her client dead, Sherlock determines that he had been poisoned.

Holmes and Watson find themselves digging through the dark world of the mob to find a killer when they discover the body of a former assassin.

Captain Gregson's team learns a bit about his personal life after his home is invaded. Holmes and Watson track the gunman.

Sherlock's brother, Mycroft, arrives in New York and enlists Holmes and Watson to help solve a case involving his former fiancee. Meanwhile, Sherlock has a difficult time accepting Mycroft and Joan's relationship.

When a young woman is murdered and it is discovered that she is a "kept woman", Holmes and Watson investigate her ties to a billionaire CEO.

Holmes and Watson uncover the identity of a serial killer whose case has gone cold and find themselves butting heads with the NYPD.

When an investigation goes horribly wrong, Sherlock must testify in an official police inquiry which jeopardizes his and Watson's future with the NYPD.

When a hedge fund manager who was also running a pyramid scheme is murdered, Holmes and Watson must determine which of his clients is guilty. Also, Sherlock contemplates sponsoring a fellow recovering addict.

The kidnapping of a young girl leads Holmes and Watson to a familiar face from the past.

When a body is found in a barrel, Holmes and Watson launch an investigation into the Mafia's ties to the murder. Meanwhile, Sherlock attempts to make amends with Detective Bell. Featuring Peter Gerety and Paul Sorvino.

When Joan revisits one of Sherlock's cold cases, she discovers an unsolved murder is connected to a rare prehistoric fossil. Meanwhile, Sherlock finds himself in uncharted territory when his duties as a sobriety sponsor cross his ...

Tensions rise when Holmes and Watson are forced to partner with Gareth Lestrade, Sherlock's former Scotland Yard colleague, on a bombing investigation.

Holmes and Watson consult on a case in which a man suspected of murdering his wife years ago receives a ransom demand for her safe return. Meanwhile, Lestrade overstays his welcome at the brownstone and seems unwilling to leave.

When a famous cancer researcher is found dead, Holmes and Watson must determine if the scientist's untimely demise was tied to his latest cutting-edge invention. Meanwhile, Bell is finally cleared to re-enter the field.

A serial killer known for biting his victims appears to be killing again, even though he was presumed dead.

Holmes and Watson must find the source of anthrax that may be used for a terrorist attack.

When Sherlock's brother Mycroft makes a surprise return to New York, his motivations cause discord between Sherlock and Joan. Meanwhile, a missing person case takes Sherlock and Joan inside the world of unmanned aeronautics.

With Watson kidnapped, the Holmes brothers are extorted to buy her back by acquiring something the gangsters greatly value. As the clock runs down on Watson's life, Sherlock is forced to work with his despised brother Mycroft.

Mycroft's handler at MI6 asks Sherlock to investigate the death of a mentally disturbed operative. Watson tries to cope with her feelings about the kidnapping, as well as Mycroft's deceptions.

Rising tension between Sherlock and Watson bring their partnership to a crossroads, but they endeavor to put their differences aside while they help Sherlock's brother, Mycroft, who faces accusations of treason and murder. Rhys If...

Holmes returns to New York with a new apprentice and a renewed interest in working with the NYPD after being fired by London's MI6. Unfortunately, Joan, the NYPD's new go-to PI, must give her approval first.

When Holmes and Watson join forces on a double homicide, Sherlock's new apprentice, Kitty, threatens the investigation when she allows her jealousy of Sherlock and Joan's work rapport to override her better judgment.

Sherlock helps a math genius from his network of "Irregulars" experts after he stumbles upon a body while participating in a math puzzle competition. Meanwhile, Joan attempts to extend an olive branch after she learns about Kitty'...

An A.I. computer is suspected for the murder of its creator; Sherlock and the team go to work to solve the case.

Sherlock and Kitty investigate after a man's severed hand is found in the street; Gregson gets in trouble with the brass and his daughter when he punches another cop; Sherlock discovers a manuscript that Watson has written about h...

Holmes and Watson search for a thief who committed murder to steal a rare map. Meanwhile, Watson becomes concerned with Sherlock's escalating interference into Kitty's burgeoning personal life.

A bored Sherlock forces his investigative services onto Joan, who is trying to locate a woman who has been missing for five years, and the only clue is the smell of nutmeg at the site of her disappearance. Meanwhile, Joan's bond w...

Holmes and Watson join forces with the NYPD after a police officer is murdered. Also, Sherlock searches for the creator of a "recovery blog" who is posting personal statements he has made in sobriety meetings.

When a nurse Watson used to work with asks for her help finding their missing acquaintance, the woman's trail leads Watson and Holmes to another person who has disappeared. Also, Sherlock struggles with his sobriety when he finds ...

While Kitty tries to find a runaway teen, Sherlock and Joan work a case in which the murder of a brilliant bioengineer looks to be at the hands of a drug cartel. Also, Joan makes a major life decision but worries it will impact Sh...

Watson starts her new job as an investigator for an insurance firm, but ends up joining forces on a case with Sherlock when a threat to Kitty emerges.

As Kitty begins to unravel due to the imminent threat to her safety, Sherlock and Joan intensify their efforts to help her. Also, the origin of Sherlock and Kitty's relationship is revealed.

Holmes and Watson are faced with a very large suspect pool when a debt collector is murdered; Andrew wants Watson to meet his father.

Sherlock and Detective Bell investigate the kidnapping of two zebras from the zoo.

Holmes and Watson follow a blood trail into the world of wrongful death compensation when they investigate a series of murders in which the killer leaves envelopes of cash on the victims. Also, Holmes makes a generous gesture towa...

Holmes investigates himself when he becomes a suspect in a murder that took place during the height of his addiction; clues make Holmes question his innocence.

A murder victim turns out to have been instantly frozen at the time of death; Watson is forced to have an awkward conversation with her brother after learning he is having an affair.

A driver for a ride sharing company is intentionally run over by a city cab, Sherlock and Joan wonder if it's a case of professional jealousy. A romance Sherlock has with a longtime Irregular complicates when she makes a shocking ...

Holmes and Watson are drawn into an Internet war when a member of the hacker group Everyone is murdered.

Holmes and Watson investigate the murder of a professional skeptic, a man who debunked paranormal, religious and scientific phenomenon for a living. The case becomes urgent when his homicide reveals a potential threat to homeland ...

Two New York City paramedics are shot and their ambulance with its patient is abducted by the murderer. Holmes and Watson join the manhunt to find out what happened and why. Holmes learns information about Alfredo, which strains t...

When a judge is murdered, Holmes and Watson become involved in the interstate search to find the prime suspect, an escaped convict from a privatized prison. Also, when Holmes applies his deductive reasoning to Detective Bell's new...

A researcher - one of Sherlock's fellow beekeepers - who was investigating a deadly honeybee outbreak is killed; Capt. Gregson asks Watson for help with an unofficial investigation that helps him make a decision.

Sherlock faces the consequences of his actions, including the arrival of his father. While waiting for word from the DA, Holmes and Watson investigate a cold case at the behest of the lead suspect, who makes a request Holmes can't...

Sherlock and Holmes consult with the FBI on a multiple homicide case involving a DARPA sponsored lab.

Sherlock and Watson are back working with the NYPD on a double homicide involving a doppelganger of the intended victim. Sherlock offers his consulting services to his father, to help him finish his business in New York.

When Holmes and Watson investigate the murder of a fertility lab technician, they discover the woman had a secret personal life that leads them to multiple suspects. Also, the tables are turned on Watson when she's investigated by...

Sherlock and Joan investigate the murder of a struggling archaeologist who was seemingly killed for some vintage video games he unearthed.

Morland offers to act as one of his son's "Irregular" consultants so that he can lend Sherlock and Joan his considerable resources to help them solve a case.

The duo goes against a clever opponent, who forces Holmes to think out of the box. Meanwhile Watson's troubles with her father are brought into focus when he writes a book about her and Holmes.

Sherlock thinks Watson and Det. Bell are having an affair. A series of apparently connected events occur after a murder which forces the detective to question his own theory at every step.

A Russian billionaire is assassinated in New York and Holmes and Watson embark upon several instances of hacking and weaponory business. Meanwhile, a secret about Morland, Sherlock's father is revealed.

A social worker asks Holmes and Watson to investigate a private college, when she becomes convinced that they have murdered one of her colleagues.

When evidence at the morgue is destroyed, suspicion falls on emerging gangs. Holmes believes that identifying a Jane Doe will help him unlock the case, while Watson deals with the reappearance of an old adversary.

Sherlock is recruited to heist a computer from a violent meth dealing motorcycle gang. While a former suspect from a previous case asks Joan to run a background check on her new boss.

When a gathering of mushroom aficionados are found dead, Holmes and Watson must explore an array of botanists, biochemists, academics and stoners for a poisoner.

Holmes investigates the assassination attempt on his father while trying to solve the triple homicide of Chinese gangsters. A secret about Sherlock's mother is revealed.

When Watson runs into Captain Gregson and his secret girlfriend, a former NYPD officer, she inadvertently sets the couple's breakup in motion. Also, Holmes and Watson investigate the murder of a wealthy woman who left her consider...

At the urging of Morland's wealthy associate, Henry Baskerville (Tom Everett Scott), Holmes and Watson look into the death of his brother and discover that a witness saw the man chased to his death by a large, glowing animal too f...

When a vigilante dressed as a comic book hero is murdered, it's up to Holmes and Watson to find the man's true identity and locate his killer; Moreland tries to charm Watson into doing him a favor.

Holmes and Watson investigate a burglary at an illegal high stakes poker game held by Mycroft's ex girlfriend. Watson is suspicious of their employer.

Holmes and Watson investigate the murder of a young woman whose college selfie was turned into a piece of contemporary art. Watson tries to get closer to her half-sister.

Holmes and Watson investigate a double murder which is not what it first appears.

Sherlock's father, Morland (John Noble), becomes Sherlock and Joan's prime suspect in a murder investigation after one of his employees is killed under the guise of a robbery.

Sherlock's suspicions concerning Moriarty's handiwork turn out to be true and her evil successor is revealed. Morland's desire for vengeance causes Sherlock to consider just which brand of justice this new villain warrants.

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